Use of balloon catheter dilation vs. traditional endoscopic sinus surgery in management of light and severe chronic rhinosinusitis of the frontal sinus: a multicenter prospective randomized study

OBJECTIVE: Chronic rhinosinusitis (CRS) of the frontal sinus is a complex pathological condition and many surgical techniques were described to treat this area endoscopically, like traditional endoscopic sinus surgery (ESS) and balloon catheter dilation (BCD). PATIENTS AND METHODS: We designed a multicenter prospective randomized study to assess the validity and safety of BCD vs. ESS in symptomatological chronic rhinosinusitis of the frontal sinus enrolling a population of 102 adult patients (64 men and 38 women; overall 148 frontal sinuses studied) with non-polypoid CRS. For a better evaluation of the disease, in our study we decided to analyze both radiological (Lund-McKay CT scoring modified by Zinreich) and symptomatological results (SNOT-20 questionnaire). We divided the population affected in two groups, one with light/mild frontal CRS and the other with moderate/severe frontal CRS, basing on radiological findings at Lund-MacKay modified by Zinreich score. Every group was divided in two subgroups, in one we used BCD and in the other we used traditional ESS. RESULTS: The current literature does not support the suggestion that indications for BCD and ESS are identical, and additional research is needed to determine the role for BCD in specific patient populations. The results showed a not statistically significative difference between BCD and conventional ESS of the frontal sinus in patients with light/mild CRS and in patients with moderate/severe CRS at Lund-Mackay modified by Zinreich score. The same not statistically significative difference was observed comparing the results of SNOT-20 questionnaire in the group of light/mild frontal chronic rhinosinusitis. However, we noticed a statistically significant better outcome of SNOT-20 score in patients with moderate/severe chronic rhinosinusitis that underwent BCD of frontal sinus compared to ESS. CONCLUSIONS: BCD and ESS are two alternative weapons in the baggage of every endoscopic surgeon, even because they present similar outcomes, safeness and effectiveness both in light/mild and moderate/severe chronic rhinosinusitis of the frontal sinus. An interesting result of our study was the statistically significant better outcome of SNOT-20 score in patients that underwent BCD of frontal sinus for a moderate/severe CRS, compared to those that underwent a traditional ESS

A Power-Efficient Methodology for Mapping Applications on Multi-Processor System-on-Chip Architectures

This work introduces an application mapping methodology and case study for multi-processor on-chip architectures. Starting from the description of an application in standard sequential code (e.g. in C), first the application is profiled, parallelized when possible, then its components are moved to hardware implementation when necessary to satisfy performance and power constraints. After mapping, with the use of hardware objects to handle concurrency, the application power consumption can be further optimized by a task-based scheduler for the remaining software part, without the need for operating system support. The key contributions of this work are: a methodology for high-level hardware/software partitioning that allows the designer to use the same code for both hardware and software models for simulation, providing nevertheless preliminary estimations for timing and power consumption; and a task-based scheduling algorithm that does not require operating system support. The methodology has been applied to the co-exploration of an industrial case study: an MPEG4 VGA real-time encoder

Reconfigurable Computing and Hardware/Software Codesign

none3Article ID 731830 - EditorialPLAKS T. P; SANTAMBROGIO M. D; D. SCIUTOPLAKS T., P; Santambrogio, MARCO DOMENICO; Sciuto, Donatell

Efficient Hardware Design Of Iterative Stencil Loops

A large number of algorithms for multidimensional signals processing and scientific computation come in the form of iterative stencil loops (ISLs), whose data dependencies span across multiple iterations. Because of their complex inner structure, automatic hardware acceleration of such algorithms is traditionally considered as a difficult task. In this paper, we introduce an automatic design flow that identifies, in a wide family of bidimensional data processing algorithms, sub-portions that exhibit a kind of parallelism close to that of ISLs; these are mapped onto a space of highly optimized ad-hoc architectures, which is efficiently explored to identify the best implementations with respect to both area and throughput. Experimental results show that the proposed methodology generates circuits whose performance is comparable to that of manually-optimized solutions, and orders of magnitude higher than those generated by commercial HLS tools

Earned schedule formulation using nonlinear cost estimates at completion

This work contributes to improving available methodologies for duration and cost estimates of ongoing projects with nonlinear cost profiles. It is demonstrated that accurate time estimates can be made when a generalized mathematical formulation of the Earned Schedule and the point estimate methodology are used. It also highlights the advantages of using these duration estimate methodologies to provide more accurate nonlinear schedule-based cost estimates at completion. This is shown via application and comparison of the proposed methodologies to datasets of eight real case projects from the construction industry. In particular, the defined methodologies tend to perform better, on average, than traditional index-based formulae, especially in the early stages of project development when the practical benefits are the greatest for project teams to take their corrective actions